Pilot & production-scale glass reactors - chemReactor CR

High-performance reactor systems for API synthesis, small-scale production and pilot plant applications
Volume: 15 / 30 / 60 / 100 / 160 / 250 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass lined steel / PTFE / PFA / Tantalum
Hastelloy® or other materials and other designs on request

The CR type chemReactor is a multipurpose pilot reactor system for chemical process development, scale-up, process simulation and kilo-scale cGMP production in batch and semi-batch operation.

Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems: The inert materials allow safe processing in an inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup.

The chemReactor CR system consists of:

• Reactor: with solid jacketed glass lined steel bottom stands for solid construction, excellent heat transfer, stable process conditions and temperatures, and a glass section to easily improve and control chemical reactions by visual observation.
• Distillation glass overhead: built with buchiflex components (unique flexible ball - socket joints) for multiple, reliable processes under full vacuum.

Typical applications:

• Chemical synthesis
• Extraction / evaporation
• Purification / crystallization
• Separation
• API manufacturing
• Peptide production
• Process development
• Scale-up
• Cryogenic reactions
• Small scale production
• Pilot plant / kilo lab